Nope, the 2nd# uses its own savedata but has the ability to convert those of the 2nd to continue the game that you have saved there (if the first time you play the 2nd# it detects saves from the 2nd it will ask you if you want to use them), but the 2nd is not able to use the saves from 2nd# Regards =D
Ah, I forgot to mention, the 2nd# has improvements that are not present in the 2nd, for example it is only necessary to scan the Memory Stick for DLC content once from the options menu (same as Extend) while the 2nd scans it every time you open the extra content menu... But except for the improvements and the saves they are still the same games...